Additional assignment of the human 5S rRNA genes to chromosome region 1q31
| Autor: | J N Nielsen, B Lomholt, C Hallenberg, Sune Frederiksen |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Genetics
RNA Ribosomal 5S Chromosome Mapping Chromosomal translocation RNA Probes Biology Ribosomal RNA Molecular biology Gene mapping Chromosomes Human Pair 1 Chromosome regions Humans Internal transcribed spacer Molecular Biology Metaphase Ribosomal DNA Chromosome 22 In Situ Hybridization Genetics (clinical) |
| Zdroj: | Cytogenetic and Genome Research. 70:76-79 |
| ISSN: | 1424-859X 1424-8581 |
| DOI: | 10.1159/000133996 |
| Popis: | A major fraction of the human 5S rRNA genes has previously been assigned to chromosome region 1q42.11→q42.13 (Sørensen et al., 1991). Through in situ hybridization of different tritiated probes to metaphase spreads, we have demonstrated that a minor fraction of the 5S rRNA genes is localized at band lq31. This fraction amounts to 25–30% of the genes found in the region 1q42.11→q42.13. Results obtained with the chromosomes of a balanced translocation carrier involving this region indicate that the major cluster is localized in band 1q42.13. |
| Databáze: | OpenAIRE |
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