Association of Gastrointestinal Hemorrhage with Increased Blood Urea Nitrogen and BUN/Creatinine Ratio in Dogs: A Literature Review and Retrospective Study
| Autor: | Gregory F. Grauer, Lauren C. Prause |
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| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Creatinine General Veterinary urogenital system business.industry Retrospective cohort study medicine.disease Gastroenterology Surgery Teaching hospital chemistry.chemical_compound chemistry Melena Internal medicine Medicine Serum creatine Azotemia medicine.symptom business Increased blood urea nitrogen Blood urea nitrogen |
| Zdroj: | Veterinary Clinical Pathology. 27:107-111 |
| ISSN: | 1939-165X 0275-6382 |
| DOI: | 10.1111/j.1939-165x.1998.tb01028.x |
| Popis: | Blood urea nitrogen (BUN) and serum creatine concentrations were recorded from the medical records of 52 dogs with clinical evidence for upper gastrointestinal hemorrhage (UGH) at the Colorado State University Veterinary Teaching Hospital between 1988 and 1995. Eighteen of the dogs had melena, 11 dogs had hematemesis, and 23 dogs had both melena and hematemesis. Compared with age-matched control dogs, dogs with suspected UGH had a significantly higher BUN concentration (31.0 mg/dL vs. 16.5 mg/dL), creatinine concentration (1.2 mg/dL vs. 1.1 mg/dL) and BUN/creatinine ratio (27.6 vs. 14.4). The increase in BUN/creatinine ratio suggested that the increased BUN concentration in dogs with evidence for UGH primarily was associated with increased gastrointestinal absorption of nitrogenous compounds, and hepatic ureagenesis. |
| Databáze: | OpenAIRE |
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