SWIR, Thermal and CP-OCT imaging probes for the in vivo assessment of the activity of root caries lesions
Autor: | Vincent B. Yang, Nai-Yuan N. Chang, Wiliiam A. Fried, Cynthia L. Darling, Prajna Banan, Jacob C. Simon, Yihua Zhu, Daniel Fried, Oanh Thi Tu Le, Donald A. Curtis |
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Přispěvatelé: | Rechmann, Peter, Fried, Daniel |
Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
CP-OCT
root caries Bioengineering Article Lesion SWIR imaging Optical coherence tomography In vivo lesion activity Clinical Research medicine thermal imaging Root caries Cancer screening and diagnosis medicine.diagnostic_test business.industry Thermal emission Lesion depth Detection Structural composition Biomedical Imaging medicine.symptom business Nuclear medicine 4.2 Evaluation of markers and technologies |
Zdroj: | Proc SPIE Int Soc Opt Eng |
Popis: | New imaging technologies are needed for the clinical assessment of lesions on root surfaces. It is not sufficient to simply detect caries lesions; methods are needed to assess lesion depth, structural composition and activity to determine if chemical intervention has the potential to be effective and if remineralization has occurred. Lesions were monitored using CP-OCT during lesion dehydration to assess the lesion structure and any shrinkage. Thermal imaging at 6-10 μm wavelengths and short wavelength-IR imaging at 1450-1750-nm were used to monitor thermal emission during lesion dehydration to assess lesion activity. Imaging probes were custom fabricated for clinical use. We present the first clinical results of a small feasibility study employing CP-OCT, thermal and SWIR imaging to assess lesion activity in vivo on thirty test subjects with suspected root caries lesions. |
Databáze: | OpenAIRE |
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