Mass efficiency of alkene syntheses with tri- and tetrasubstituted double bonds
| Autor: | Marco Eissen, Dieter Lenoir |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
Double bond Geminal Olefin metathesis 010405 organic chemistry Renewable Energy Sustainability and the Environment Alkene Negishi coupling General Chemical Engineering General Chemistry Mass efficiency 010402 general chemistry 01 natural sciences Coupling reaction 0104 chemical sciences Catalysis chemistry Computational chemistry Alkenes Eatos Environmental Factor Process Mass Intensity Waste Prevention Environmental Chemistry Organic chemistry |
| Zdroj: | ACS Sustainable Chem. Eng. 5, 10459-10473 (2017) |
| Popis: | Environmental factors and process mass intensity were determined and evaluated for more than 30 standard procedures for the synthesis of alkenes with tri- and tetrasubstituted double bonds. They contain some of the most commonly used reaction types for the synthesis of alkenes, e.g., Peterson, Shapiro, Heck, Suzuki, and Negishi. Four kinds of syntheses of geminal dihalides were also considered. The highest efficiency is found when employing the olefin metathesis reaction followed by other modern catalytic processes, and the lowest efficiency is found with the Julia–Lythgoe process. Several types of McMurry coupling reactions show that the efficiency is dependent on the variant of this type of reaction. These metrics point out weaknesses as well as optimization potentials and show which performances can be expected. This could provide an orientation when mass efficiency aspects are relevant during the synthesis planning of alkenes with tri- and tetrasubstituted double bonds. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|