Diastereoselective self-assembly of chiral diamine-chelated aryllithiums to dimeric aggregates
| Autor: | Arink, Anne M., Kronenburg, Claudia M. P., Jastrzebski, Johann T. B. H., Lutz, Martin, Spek, Anthony L., Gossage, Robert A., Van Koten, Gerard, Sub Organic Chemistry and Catalysis, Sub Crystal and Structural Chemistry, Sub Algemeen FBW |
|---|---|
| Přispěvatelé: | Sub Organic Chemistry and Catalysis, Sub Crystal and Structural Chemistry, Sub Algemeen FBW |
| Rok vydání: | 2004 |
| Předmět: |
chemical reaction
Stereochemistry diastereoisomer Dimer chirality Crystal structure Biochemistry Catalysis lithium derivative chemistry.chemical_compound Colloid and Surface Chemistry Diamine Molecule diamine dimerization Diastereomer article molecular weight General Chemistry solid state X ray crystallography dimer reaction analysis Monomer chemistry International molecular interaction Organic synthesis Chirality (chemistry) combinatorial chemistry |
| Zdroj: | Journal of the American Chemical Society, 126(49), 16249. American Chemical Society |
| ISSN: | 0002-7863 |
| Popis: | Aryllithium compounds [LiC6H4(CH2N(Et)CH2CH2NEt2)-2]2 (2b), [LiC6H4(CH(Me)N(Me)CH2CH2NMe2-(R))-2]2 ((R)-3b), and [LiC6H4(CH(Me)N(Me)CH2CH2NMe2-(rac))-2]2 ((rac)-3b) were synthesized and characterized in the solid state and in solution. X-ray crystallographic studies of 2b and (R)-3b and molecular weight determinations of 2b, (R)-3b, and (rac)-3b by cryoscopy in benzene showed that, both in the solid state and in apolar, noncoordinating solvents such as benzene, these compounds exist as discrete dimeric aggregates. For (R)-3b and (rac)-3b the aggregation process of two monomeric aryllithium units to one dimer is highly diastereoselective. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|