Volumetric decrease of pancreas after abdominal irradiation, it is time to consider pancreas as an organ at risk for radiotherapy planning
| Autor: | Tamer Baysal, Sevim Ozdemir, Gokhan Yaprak, Hazan Ozyurt, Cengiz Gemici, Ozgur Ozan Seseogullari |
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| Přispěvatelé: | Biruni Üniversitesi, Tıp Fakültesi |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
Male Organs at Risk medicine.medical_specialty Radiotherapy planning medicine.medical_treatment lcsh:R895-920 Normal tissue Adenocarcinoma lcsh:RC254-282 03 medical and health sciences Organ at risk 0302 clinical medicine Stomach Neoplasms Abdomen medicine Humans Radiology Nuclear Medicine and imaging Abdominal radiotherapy Radiation treatment planning Abdominal irradiation Radiation Injuries Pancreas Volumetric shrinkage business.industry Research Radiotherapy Planning Computer-Assisted Radiotherapy Dosage Exocrine insufficiency Middle Aged lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Prognosis Endocrine insufficiency Radiation therapy medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Female Radiotherapy Adjuvant Radiology Radiotherapy Intensity-Modulated business Follow-Up Studies |
| Zdroj: | Radiation Oncology (London, England) Radiation Oncology, Vol 13, Iss 1, Pp 1-7 (2018) |
| ISSN: | 1748-717X |
| Popis: | Background Volumetric shrinkage of normal tissues such as salivary glands, kidneys, hippocampus are observed after radiotherapy. We aimed to assess the alterations in pancreatic volume of patients who received abdominal radiotherapy and define pancreas as an organ at risk for radiation treatment planning. Material-methods Forty-nine patients operated for gastric adenocarcinoma who received adjuvant abdominal radiotherapy were in the study group, 27 patients with early stage disease who did not need adjuvant treatment after surgery comprised the control group. An experienced radiologist contoured the pancreas of all the patients from computed tomographies imported to the planning system obtained either for radiation planning purpose or for follow-up after surgery. The same procedure was repeated one year later for both groups. Measured volume of the pancreas was expressed in cm3. Results Mean pancreatic volumes were similar in both groups at the onset of the study, 51,34 ± 20,33 cm3, and 50,12 ± 23,75 cm3 in the irradiated and the control groups respectively (p = 0,63). One year later, mean pancreatic volumes were significantly decreased in each group; 22,48 ± 10,53 cm3, 44,18 ± 23,08 cm3 respectively, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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