Large‐scale GWAS in sorghum reveals common genetic control of grain size among cereals
| Autor: | Xuemin Wang, Emma S. Mace, Erik van Oosterom, Alan Cruickshank, Xianrong Zhao, Adrian Hathorn, Ian D. Godwin, Yongfu Tao, Colleen H. Hunt, David Jordan |
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| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
0301 basic medicine QTL Quantitative Trait Loci Population Genome-wide association study Plant Science Quantitative trait locus 01 natural sciences 03 medical and health sciences orthologues GWAS education Genetic Association Studies Sorghum Research Articles Panicle grain size education.field_of_study biology cereal crops food and beverages biology.organism_classification Grain size Genetic architecture Phenotype 030104 developmental biology Agronomy Seeds Trait Agronomy and Crop Science Research Article 010606 plant biology & botany Biotechnology |
| Zdroj: | Plant Biotechnology Journal |
| ISSN: | 1467-7652 1467-7644 |
| DOI: | 10.1111/pbi.13284 |
| Popis: | Summary Grain size is a key yield component of cereal crops and a major quality attribute. It is determined by a genotype’s genetic potential and its capacity to fill the grains. This study aims to dissect the genetic architecture of grain size in sorghum. An integrated genome‐wide association study (GWAS) was conducted using a diversity panel (n = 837) and a BC‐NAM population (n = 1421). To isolate genetic effects associated with genetic potential of grain size, rather than the genotype’s capacity to fill the grains, a treatment of removing half of the panicle was imposed during flowering. Extensive and highly heritable variation in grain size was observed in both populations in 5 field trials, and 81 grain size QTL were identified in subsequent GWAS. These QTL were enriched for orthologues of known grain size genes in rice and maize, and had significant overlap with SNPs associated with grain size in rice and maize, supporting common genetic control of this trait among cereals. Grain size genes with opposite effect on grain number were less likely to overlap with the grain size QTL from this study, indicating the treatment facilitated identification of genetic regions related to the genetic potential of grain size. These results enhance understanding of the genetic architecture of grain size in cereal, and pave the way for exploration of underlying molecular mechanisms and manipulation of this trait in breeding practices. |
| Databáze: | OpenAIRE |
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