Subgingival temperature: relation to gingival crevicular fluid enzymes, cytokines, and subgingival plaque micro-organisms
| Autor: | Q. T. Smith, Larry F. Wolff, Ambika Mathur, Nancy J. Koller, Dorothee M. Aeppli |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Gingival and periodontal pocket Dental Plaque Gingiva Gingival Hemorrhage Alpha interferon Dental plaque Aggregatibacter actinomycetemcomitans Prevotella intermedia Body Temperature Gingivitis Interferon-gamma Eikenella corrodens Periodontal Attachment Loss medicine Humans Periodontal Pocket Periodontitis Aged Glucuronidase Peroxidase Fusobacterium nucleatum business.industry Dental Plaque Index Gingival Crevicular Fluid Middle Aged medicine.disease Cross-Sectional Studies Clinical attachment loss Periodontics Cytokines Female medicine.symptom Periodontal Index business Leukocyte Elastase Porphyromonas gingivalis Interleukin-1 |
| Zdroj: | Journal of clinical periodontology. 24(12) |
| ISSN: | 0303-6979 |
| Popis: | There have been no reports on the relationship of subgingival temperature to specific gingival crevicular fluid (GCF) components. Therefore, the purpose of this cross-sectional study was to determine whether there was any relationship between subgingival temperature and GCF levels of neutrophil elastase (NE), myeloperoxidase (MPO), beta-glucuronidase (BG), interleukin-1 alpha (IL-1), and interferon alpha (IFN). Furthermore, another objective was to confirm an association of subgingival temperature with clinical parameters and specific subgingival plaque micro-organisms as has been reported earlier. 27 human subjects each having healthy (n = 50), gingivitis (n = 59) and periodontitis (n = 53) sites were evaluated. The plaque index (PI), subgingival temperature, probing depth, attachment loss, bleeding index and gingival index were measured. GCF was sampled following the measurement of the PI and removal of the supragingival plaque. GCF samples were assayed for the enzymes NE, BG, MPO and the cytokines IFN-alpha and IL-1 alpha. A sterile Gracey curette was utilized at each sampled site to collect subgingival plaque. The plaque samples were evaluated using an immunoassay. Subgingival temperature was found to directly correlate with all clinical parameters (p0.001). Significant, albeit not large, correlations were found between subgingival temperature and NE (r = 0.35, p0.001), MPO (r = 0.26, p0.001) and BG (r = 0.23, p0.01). Temperature was found to correlate positively with E. corrodens (r = 0.33, p0.02) and F. nucleatum (r = 0.25, p0.05) but not with P. intermedia (r = 0.02, p = 0.9), P. gingivalis (r = 0.20, p = 0.1) and A. actinomycetemcomitans (r = 0.01, p0.9). In conclusion, subgingival temperature is correlated with the GCF enzymes, NE, MPO and BG as well as the clinical parameters and specific plaque micro-organisms associated with periodontal disease. |
| Databáze: | OpenAIRE |
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