New flavane gallates isolated from the leaves of Plicosepalus curviflorus and their hypoglycemic activity

Autor:	Shagufta Perveen, Ghada Ahmed Fawzy, Areej Mohammad Al-Taweel, Kamal E.H. El Tahir, Saleh I. Alqasoumi
Rok vydání:	2012
Předmět:	Pharmacology Traditional medicine biology Molecular Structure Stereochemistry General Medicine Loranthaceae biology.organism_classification Plant Leaves chemistry.chemical_compound chemistry Gallic Acid Drug Discovery Gallic acid Plicosepalus Pomolic acid Plicosepalus curviflorus Quercetin Lupeol
Zdroj:	Fitoterapia. 83(8)
ISSN:	1873-6971
Popis:	Two new flavane gallates were isolated from the leaves of Plicosepalus curviflorus. The structure of the new compounds was established as 2S,3R-3,3',4',5,7-pentahydroxyflavane-5-O-gallate (1) and 2S,3R-3,3',4',5,5',7-hexahydroxyflavane-4',5-di-O-gallate (2), respectively. In addition, seven known compounds (-)-catechin (3), quercetin (4), lupeol (5), β-sitosterol (6), pomolic acid (7), β-sitosterol 3-O-β-d-glucopyranoside (8) and 4-methoxycinnamic acid (9) were reported for the first time from the genus Plicosepalus. Compounds 1, 2 and 3 were investigated for their hypoglycemic activity and showed significant hypoglycemic activity in Swiss Albino mice.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff92b1a84abaa1ce6a19c7aaaa4bc88 https://pubmed.ncbi.nlm.nih.gov/22986293 Zobrazit plný text záznamu Full Text from ScienceDirect