Evaluation of Dynamic Thiol/Disulphide Homeostasis in Patients with Periodontitis
| Autor: | Cemil Nural, Meral Günhan, Ceylan Bal, Mahmure Ayşe Tayman |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
non-surgical periodontal treatment
Periodontitis lcsh:R5-920 medicine.medical_specialty Chemistry lcsh:R lcsh:Medicine medicine.disease Endocrinology Internal medicine medicine oxidative stress In patient thiol/disulphide homeostasis lcsh:Medicine (General) Thiol disulphide homeostasis periodontitis |
| Zdroj: | Meandros Medical and Dental Journal, Vol 22, Iss 1, Pp 41-49 (2021) |
| ISSN: | 2149-9063 |
| DOI: | 10.4274/meandros.galenos.2020.14622 |
| Popis: | Objective:Thiols are antioxidant organic compounds with sulfhydryl group. Dynamic thiol/disulphide homeostasis is considered a marker of oxidative stress. This study aimed to determine disulphide and thiol levels in patients with generalised stage III grade C periodontitis and to investigate the relationship between biochemical and clinical periodontal parameters, namely, bleeding on probing (BOP), clinical attachment level (CAL) and probing pocket depth (PPD).Materials and Methods:Forty-eight individuals participated in the study (control, n=23; periodontitis, n=25). BOP, CAL and PPD values of the groups were recorded before and after non-surgical periodontal treatment. Thiol disulphide homeostasis was assessed by an automatic and a new spectrophotometric method. Percentages of disulphide/total thiol, disulphide/native thiol and native thiol/total thiol were calculated.Results:The clinical periodontal parameters of the periodontitis group were higher (p |
| Databáze: | OpenAIRE |
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