| Autor: |
Indranil Mitra, Klaus Bo Mogensen, Stephen C. Jacobson, Brett W. Hildenbrand, Jörg Peter Kutter, Zhenning Tan, Kaimeng Zhou, P. Nunes, Zachary D. Harms, Adam Zlotnick |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Analytical chemistry. 83(24) |
| ISSN: |
1520-6882 |
| Popis: |
We report fabrication and characterization of nanochannel devices with two nanopores in series for resistive-pulse sensing of hepatitis B virus (HBV) capsids. The nanochannel and two pores are patterned by electron beam lithography between two microchannels and etched by reactive ion etching. The two nanopores are 50-nm wide, 50-nm deep, and 40-nm long and are spaced 2.0-μm apart. The nanochannel that brackets the two pores is 20× wider (1 μm) to reduce the electrical resistance adjacent to the two pores and to ensure the current returns to its baseline value between resistive-pulse events. Average pulse amplitudes differ by |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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