| Autor: |
Joseph R. Hartmann, Louis S. McKeever, Christopher J. White, Patrick J. Whitlow, Elaine L. Enger, William W. O'Neill |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Journal of the American College of Cardiology. 25:149A-150A |
| ISSN: |
0735-1097 |
| DOI: |
10.1016/0735-1097(95)92075-g |
| Popis: |
One hundred seven patients with chronically occluded aortocoronary bypass grafts were enrolled in the ROBUST trial to determine the safety and efficacy of low dose, long-term urokinase intracoronary infusions in recanalizing these vessels. Initial patency rate was 69% and 6 month patency was 47%. The relationship between site of angioplasty following successful lysis and 6 month graft patency was reviewed. Patients with angioplasty at the distal anastomosis had an 88% acute patency rate vs 85% at sites within the graft. Six month patency was 25% for distal anastomosis and 50% for intragraft sites. Although distal graft and distal anastomosis vs origin, proximal, or mid graft acute patency rates were the same (85%), 6 month patency was 32% vs 59%. Conclusion Chronically occluded vein grafts with culprit lesions in the proximal or mid graft have a greater 6 month patency rate following recanalization with long germ intragraft urokinase infusion than when the lesion is in the distal graft or anastomosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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