Development of scientifically justified proposals on the prevention and treatment of environmentally determined constitutional growth delay in children in the West Kazakhstan region
| Autor: | Erbol Zh Bekmukhambetov, Balash T Tusupkaliev, Mairamkul B Zharlikasinova, Akmaral K Zhumalina |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Chromium Male medicine.medical_specialty Environmental Engineering Adolescent 010504 meteorology & atmospheric sciences Oil and Gas Industry Environmental pollution 010501 environmental sciences Constitutional growth delay 01 natural sciences Short stature Mining Geochemistry and Petrology Nickel compounds Environmental health Prevalence medicine Humans Environmental Chemistry Statistical analysis Child Growth Disorders 0105 earth and related environmental sciences General Environmental Science Water Science and Technology business.industry Public health Bone age Environmental Exposure General Medicine Hormones Kazakhstan Blood chemistry Metals Case-Control Studies Female medicine.symptom Environmental Pollution business |
| Zdroj: | Environmental Geochemistry and Health. 41:1251-1265 |
| ISSN: | 1573-2983 0269-4042 |
| DOI: | 10.1007/s10653-018-0210-0 |
| Popis: | Environmental pollution in many regions of Kazakhstan poses a threat to the growth and development of local children. For children living the near the Aral Sea, chrome processing and gas processing regions, we undertook a medical examination, including physical and sexual development parameters, laboratory studies (complete blood count, urinalysis, blood chemistry), bone age, blood levels of microelements (chromium, manganese, nickel, lead, copper) and hormones [thyroid (T3, T4, TSH), sexual (LH, FSH), growth (STH, IGF-1)], in consultation with relevant specialist doctors. Statistical analysis showed a significant prevalence of short stature among children living, on average, 22.9 versus 7.8% in the control region. Children in these regions have high blood levels of toxic chromium, manganese, lead and nickel compounds. The main causes of short stature in children living in the Aral Sea, chrome processing and oil and gas processing regions are cerebral-endocrine pathologies, hereditary diseases, somatogenic diseases, constitutional growth delay, a toxic chemical load and ecologically determined short stature. A working classification of short stature in children living in the Aral Sea, chrome processing and gas processing regions, including ecologically dependent short stature, has been developed. The scheme of medical and recreational measures for children living in the Aral Sea, chrome processing and gas processing regions was proposed. |
| Databáze: | OpenAIRE |
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