The effects of prenatal HIV exposure on language functioning in Kenyan children: establishing an evaluative framework
| Autor: | Amina Abubakar, Charles R. Newton, Penny Holding, Katherine J. Alcock |
|---|---|
| Přispěvatelé: | Development and Treatment of Psychosocial Problems |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Kenya Pediatrics medicine.medical_specialty 030231 tropical medicine Population Short Report Developing country HIV Infections Biochemistry Language Development General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Pregnancy 030225 pediatrics Humans Medicine education Children Language Medicine(all) education.field_of_study business.industry Transmission (medicine) Biochemistry Genetics and Molecular Biology(all) Infant virus diseases HIV General Medicine Child development Infectious Disease Transmission Vertical 3. Good health Language development In utero Child Preschool Africa Female Rural area business Genetics and Molecular Biology(all) Clinical psychology |
| Zdroj: | BMC Research Notes, 9(1), 1. BioMed Central BMC Research Notes |
| ISSN: | 1756-0500 |
| Popis: | Background HIV infection has been associated with impaired language development in prenatally exposed children. Although most of the burden of HIV occurs in sub-Saharan Africa, there have not been any comprehensive studies of HIV exposure on multiple aspects of language development using instruments appropriate for the population. Methods We compared language development in children exposed to HIV in utero to community controls (N = 262, 8–30 months) in rural Kenya, using locally adapted and validated communicative development inventories. Results The mean score of the younger HIV-exposed uninfected infants (8–15 months) was not significantly below that of the controls; however older HIV-exposed uninfected children had significantly poorer language scores, with HIV positive children scoring more poorly than community controls, on several measures. Conclusions Our preliminary data indicates that HIV infection is associated with impaired early language development, and that the methodology developed would be responsive to a more detailed investigation of the variability in outcome amongst children exposed to HIV, irrespective of their infection status. |
| Databáze: | OpenAIRE |
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