Cardiac contractility after transplantation of autologous mononuclear bone marrow cells in patients with myocardial infarction
| Autor: | Leonid N. Maslov, Yu. S. Poponina, Vyacheslav Ryabov, Krylov Al |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Heart Ventricles Myocardial Infarction Transplantation Autologous Peripheral blood mononuclear cell General Biochemistry Genetics and Molecular Biology Cell therapy Contractility Electrocardiography Internal medicine medicine Humans Ventricular Function In patient cardiovascular diseases Myocardial infarction Aged Bone Marrow Transplantation business.industry General Medicine Middle Aged medicine.disease Myocardial Contraction Transplantation medicine.anatomical_structure cardiovascular system Cardiology Female Bone marrow business Perfusion |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 141:124-128 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-006-0111-6 |
| Popis: | Autologous bone marrow mononuclear cells were transplanted by intracoronary infusion to patients with myocardial infarction after recovery of coronary perfusion. Controls received traditional therapy alone. Echocardiography was carried out before and 3 and 6 months after cell therapy. Cell transplantation did not appreciably improved left-ventricular contractility in comparison with the control group. In none patient cell therapy provoked malignant ventricular arrhythmias. Intracoronary infusion of bone marrow mononuclear cells in patients with myocardial infarction did not improve cardiac contractility and did not aggravate the course of the disease. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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