Effect of peptide Vilon on the content of transforming growth factor-beta and permeability of microvessels during experimental chronic renal failure
| Autor: | A Yu Titkov, N A Gavrisheva, K L Kozlov, V. V. Malinin, A V Panchenko, T P Ses |
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| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Endothelium Peptide General Biochemistry Genetics and Molecular Biology Capillary Permeability Subcutaneous injection Transforming Growth Factor beta Internal medicine medicine Animals chemistry.chemical_classification biology business.industry Mesenteric Artery Inferior General Medicine Transforming growth factor beta Dipeptides Serum concentration Capillaries Rats Endocrinology medicine.anatomical_structure chemistry Permeability (electromagnetism) biology.protein Chronic renal failure Kidney Failure Chronic Endothelium Vascular business Homeostasis |
| Zdroj: | Bulletin of experimental biology and medicine. 139(1) |
| ISSN: | 0007-4888 |
| Popis: | We studied the effect of Vilon in rats 2, 4, and 6 months after the onset of chronic renal failure. Subcutaneous injection of Vilon significantly decreased serum concentration of transforming growth factor-beta(1) and permeability of mesenteric microvessels in rats 2 months after the onset of chronic renal failure. Our results indicate that the preparation produces a potent homeostatic effect in the early period of chronic renal failure. |
| Databáze: | OpenAIRE |
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