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Introduction: Aeroallergens are various airborne substances or inhalants, such as pollen, spores, and other biological or non-biological airborne particles that can cause allergic disorders. Inhalation or cutaneous contact with aeroallergens can trigger a release of proteins in the form of an allergic reaction on the skin and mucous membranes. Methods: This study was a qualitative retrospective study conducted in the Al-Rayan lab in Khartoum state from January 2019 to December 2020. All records with positive specific IgE to aeroallergens have been collected from Al Rayan Laboratory center. The immunoblotting technique [Euroline food gulf (IgE)] detect the IgE antibody against specific aeroallergens Result:. Ninety-nine participants were positive for the specific IgE test aeroallergens panel. Most of them were adults, and the mean age of the participants was 21.3 ± 16.3. The most prevalent aeroallergen was Timothy grass and Oak. Timothy grass was positive among (46.5%) of the patients, Cultivated rye, olive tree, and common ragweed were mainly positive in November. The test for Oak allergen came positive in November 2020, March 2020, and October 2019 with the respective percentages (64.3%, 85.7%,46.2%). The olive tree and common ragweed aeroallergen reactions came equally positive in November 2020 the most (57.1%). Moreover, the age of the participants was related to Dog and Horse aeroallergens. In addition to penicillium, children mainly tested positive for Dog, Horse aeroallergens at P values (Conclusion: This study demonstrates that the most common aeroallergens are Timothy grass and Oak, followed by cultivated rye. |