Reactivity of Human Lymphoid and Lymphoblastoid Cells with Peanut Agglutinin: Detection of a Blood Cell Subset which Lacks Detectable Membrane HLA
| Autor: | J.-J. Ballet, Nathan Sharon, Yair Reisner, M. Fellous, M. Agrapart |
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| Rok vydání: | 1980 |
| Předmět: |
Peanut agglutinin
Arachis Lymphoid Tissue T-Lymphocytes Immunology Cell Receptors Antigen B-Cell Cell Separation Human leukocyte antigen Cell Line Antigen-Antibody Reactions Immunoenzyme Techniques Blood cell Epitopes Immunoglobulin Fab Fragments Antigen HLA Antigens Pregnancy Lectins medicine Humans Child B-Lymphocytes biology Lymphoblast Lectin General Medicine Virology Molecular biology medicine.anatomical_structure Lymphatic system Child Preschool biology.protein Female Plant Lectins |
| Zdroj: | Scandinavian Journal of Immunology. 11:555-560 |
| ISSN: | 1365-3083 0300-9475 |
| Popis: | The number of cells reacting with fluorescein-labelled peanut agglutinin varies widely among human lymphoid organs. By separation techniques, reactive cells from tonsils were characterized as E-negative, non-immunoglobulin-bearing lymphocytes. In peripheral blood, the lectin reacted with a small percentage of lymphoid and monocytoid cells which lacked HLA membrane determinants but expressed the beta 2-microglobulin antigens. The latter phenotype was also found on human lymphoblastoid cell lines. Lectin binding thus provides an effective means of characterizing these cell subsets. |
| Databáze: | OpenAIRE |
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