Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR

Autor: Kim M. Newberry, Sarah Gabriël, Lian F. Thomas, Pierre Dorny, Marshall W. Lightowlers, Rc Andrew Thompson, Boualam Khamlome, Chattouphone Keokamphet, Phouth Inthavong, Charles G. Gauci, Amanda Ash, John Allen, Anna L. Okello
Rok vydání: 2015
Předmět:
0301 basic medicine
Male
Veterinary medicine
Swine
Pilot Projects
Feces
0302 clinical medicine
Taenia solium
Medicine and Health Sciences
Prevalence
Taeniasis
SOUTHEAST-ASIA
EPILEPSY
2. Zero hunger
Aged
80 and over
Anthelmintics
Swine Diseases
FOCUS
Vaccination
Cysticercosis
030108 mycology & parasitology
Middle Aged
3. Good health
medicine.drug_formulation_ingredient
PCR
Infectious Diseases
Laos
Female
HEALTH
medicine.drug
Adult
medicine.medical_specialty
Oxfendazole
Veterinary (miscellaneous)
030231 tropical medicine
CYSTICERCOSIS
Enzyme-Linked Immunosorbent Assay
Albendazole
03 medical and health sciences
PEOPLE
Environmental health
medicine
Animals
Humans
Mass drug administration
Aged
business.industry
Tropical disease
medicine.disease
Insect Science
Tropical medicine
Parasitology
Benzimidazoles
business
Zdroj: ACTA TROPICA
ISSN: 1873-6254
0001-706X
Popis: Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400 mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30 mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention.
Databáze: OpenAIRE
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