Assessing the impact of a joint human-porcine intervention package for Taenia solium control: Results of a pilot study from northern Lao PDR
Autor: | Kim M. Newberry, Sarah Gabriël, Lian F. Thomas, Pierre Dorny, Marshall W. Lightowlers, Rc Andrew Thompson, Boualam Khamlome, Chattouphone Keokamphet, Phouth Inthavong, Charles G. Gauci, Amanda Ash, John Allen, Anna L. Okello |
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Rok vydání: | 2015 |
Předmět: |
0301 basic medicine
Male Veterinary medicine Swine Pilot Projects Feces 0302 clinical medicine Taenia solium Medicine and Health Sciences Prevalence Taeniasis SOUTHEAST-ASIA EPILEPSY 2. Zero hunger Aged 80 and over Anthelmintics Swine Diseases FOCUS Vaccination Cysticercosis 030108 mycology & parasitology Middle Aged 3. Good health medicine.drug_formulation_ingredient PCR Infectious Diseases Laos Female HEALTH medicine.drug Adult medicine.medical_specialty Oxfendazole Veterinary (miscellaneous) 030231 tropical medicine CYSTICERCOSIS Enzyme-Linked Immunosorbent Assay Albendazole 03 medical and health sciences PEOPLE Environmental health medicine Animals Humans Mass drug administration Aged business.industry Tropical disease medicine.disease Insect Science Tropical medicine Parasitology Benzimidazoles business |
Zdroj: | ACTA TROPICA |
ISSN: | 1873-6254 0001-706X |
Popis: | Following confirmation that a remote village of approximately 300 inhabitants in northern Lao PDR was hyperendemic for the Neglected Tropical Disease Taenia solium, a pilot human-porcine therapeutic control intervention was implemented between October 2013 and November 2014. Mass drug administration with a three day albendazole 400 mg protocol was offered to all eligible humans in October 2013 and March 2014. At these times, and again in October 2014, eligible village pigs received the anti-cysticercosis TSOL18 vaccination and an oral dose of oxfendazole anthelmintic at 30 mg/kg, both repeated one month later. Community and individual human taeniasis prevalences were estimated via copro-antigen ELISA of volunteered human faecal samples prior to October 2013, and again in January 2015, in order to examine the short term impact of the intervention. |
Databáze: | OpenAIRE |
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