Atrial Septal Defect in Children : The Incidence and Risk Factors for Diagnosis
| Autor: | Gunnar Sjöberg, Estelle Naumburg, Petru Liuba, Anna Lindam, Gustaf Tanghöj |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures business.industry Incidence (epidemiology) Septum secundum Preterm infants Pediatrik Heart defect General Medicine atrial Pediatrics Internal medicine Pediatrics Perinatology and Child Health Cardiology medicine incidence Radiology Nuclear Medicine and imaging Surgery heart septal defects epidemiology cardiovascular diseases Cardiology and Cardiovascular Medicine business |
| Popis: | Objective: Secundum atrial septal defect (ASD II) is a common congenital heart defect, and interatrial communications among preterm children is even more common. The objective of this study was to calculate the incidence of ASD II in children, with assessment to gestational age at birth. Further, to assess maternal, prenatal and postnatal risk factors associated with ASD II among children of different gestational age at birth. Design: This national registry based retrospective incidence study was supplemented with a national case-control study, using the Swedish Register of Congenial Heart Disease, Swedish Medical Birth Register and Statistics Sweden. All children, 0-18 years of age, born in Sweden and diagnosed with an ASD II between 2010 and 2015 were included in the study and compared with children without diagnosis of ASD II. Results: The yearly overall incidence of ASD II was 150 per 100 000 live births. However, this incidence ranged from 449 per 100 000 live births to 1737 per 100 000 live births, with higher incidence among preterm children. ASD II was associated with a presence of persistent ductus arteriosus; OR = 8.11 (Cl 95% 2.80-16.69), female gender; OR = 1.39 (Cl 95% 1.18-1.63) and being small for gestational age; OR = 1.86 (Cl 95% 1.29-2.68). Born preterm was also associated with ASD II; born at 32-36 gestational children; OR = 3.21 (Cl 95% 2.46-4.19), and born |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|