MRI as an Alternative to CT-Guided Biopsy of Adrenal Masses in Patients With Lung Cancer
Autor: | Michelle S. Ginsberg, Lawrence H. Schwartz, David M. Panicek, George I. Getrajdman, Karen T. Brown, Michael E. Burt |
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Rok vydání: | 1998 |
Předmět: |
Adenoma
Adult Male Pulmonary and Respiratory Medicine medicine.medical_specialty Lung Neoplasms Biopsy Adrenal Gland Neoplasms Adrenal neoplasm Adenocarcinoma Sensitivity and Specificity Metastasis Neoplasms Multiple Primary Carcinoma Adenosquamous Carcinoma Non-Small-Cell Lung Humans Medicine Adrenal adenoma Lung cancer Aged Aged 80 and over medicine.diagnostic_test business.industry Adrenal cortex Magnetic resonance imaging Middle Aged medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Carcinoma Squamous Cell Female Surgery Radiology Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business Algorithms |
Zdroj: | The Annals of Thoracic Surgery. 65:193-197 |
ISSN: | 0003-4975 |
Popis: | Background . This study was performed to assess chemical shift magnetic resonance imaging (CSMRI) for characterizing adrenal masses in patients with lung cancer, and to compare charges associated with two algorithms for assessing adrenal masses in these patients. Methods . Forty-two patients with lung cancer underwent both CSMRI (using in-phase and opposed-phase gradient echo images) and computed tomography-guided percutaneous biopsy of adrenal masses. Adrenal-to-spleen signal intensity ratios on the opposed-phase images were correlated with histopathologic results. The normalized charges for two algorithms were compared. In algorithm A, computed tomography-guided biopsy is used first to evaluate an adrenal mass; in algorithm B, CSMRI is used first, followed by computed tomography-guided biopsy only if CSMRI findings are not diagnostic of adenoma. Results . Biopsy showed 24 (57%) adrenal adenomas and 18 (43%) metastases. Chemical shift magnetic resonance imaging was 96% sensitive for adenoma and 100% specific. The average normalized charges associated with algorithm A were $1,905 per patient versus $1,890 with algorithm B. Conclusions . Initial use of CSMRI in evaluating an adrenal mass in lung cancer patients can obviate biopsy in 55% of patients, and its charges are similar to those for performing computed tomography-guided biopsy in all patients. |
Databáze: | OpenAIRE |
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