Immunophenotyping Lymphomas in Dogs: A Comparison of Results From Fine Needle Aspirate and Needle Biopsy Samples

Autor:	Diane K. Naydan, D. J. Fisher, Peter F Moore, Linda L. Werner
Rok vydání:	1995
Předmět:	Canine Lymphoma Pathology medicine.medical_specialty General Veterinary Cluster of differentiation business.industry medicine.disease Lymphoma Immunophenotyping Needle biopsy medicine Sampling (medicine) business Fine-needle aspirate
Zdroj:	Veterinary Clinical Pathology. 24:118-123
ISSN:	1939-165X 0275-6382
DOI:	10.1111/j.1939-165x.1995.tb00951.x
Popis:	The reliability of utilizing cytologic samples for immunophenotyping canine lymphomas was evaluated by a systematic comparison of results from fine needle aspirate (FNA) to needle biopsy specimens stained by immunochemical methods. The specific reactivity of a selected panel of 12 antibodies to cell surface markers and intermediate filaments was assessed in 11 dogs by comparing cytologic to histologic samples. There was excellent correlation of results between immunostained cytologic and histologic samples. FNA sampling is a simple, noninvasive method for determining the lymphoid phenotype in canine lymphoma. In addition, this technique may be useful as a cytodiagnostic aid in differentiating lymphoid from non-lymphoid tumors and in assessing neoplastic vs. reactive or hyperplastic processes.
Databáze:	OpenAIRE
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