A Simplified Donor Risk Index for Predicting Outcome After Deceased Donor Kidney Transplantation
| Autor: | Rhiannon Birch, J. Andrew Bradley, Dave Collett, Christopher J.E. Watson, Rachel J. Johnson |
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| Rok vydání: | 2012 |
| Předmět: |
Male
Transplantation medicine.medical_specialty business.industry Proportional hazards model Concordance Hazard ratio Context (language use) medicine.disease Kidney Transplantation Risk Assessment Tissue Donors Internal medicine Diabetes mellitus medicine Humans Female Risk assessment business Kidney transplantation |
| Zdroj: | Transplantation. 93:314-318 |
| ISSN: | 0041-1337 |
| DOI: | 10.1097/tp.0b013e31823f14d4 |
| Popis: | BACKGROUND We sought to determine the deceased donor factors associated with outcome after kidney transplantation and to develop a clinically applicable Kidney Donor Risk Index. METHODS Data from the UK Transplant Registry on 7620 adult recipients of adult deceased donor kidney transplants between 2000 and 2007 inclusive were analyzed. Donor factors potentially influencing transplant outcome were investigated using Cox regression, adjusting for significant recipient and transplant factors. A United Kingdom Kidney Donor Risk Index was derived from the model and validated. RESULTS Donor age was the most significant factor predicting poor transplant outcome (hazard ratio for 18-39 and 60+ years relative to 40-59 years was 0.78 and 1.49, respectively, P |
| Databáze: | OpenAIRE |
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