The effects of central norepinephrine infusions on drinking behavior induced by angiotensin after 6-hydroxydopamine injections into the anteroventral region of the third ventricle (AV3V)
Autor: | Alan Kim Johnson, Joseph Thomas Cunningham |
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Rok vydání: | 1991 |
Předmět: |
Male
medicine.medical_specialty Hypothalamus Drinking Behavior Thirst Injections Norepinephrine (medication) Norepinephrine Internal medicine medicine Animals Oxidopamine Molecular Biology Median preoptic nucleus Injections Intraventricular Hydroxydopamine Lamina terminalis business.industry General Neuroscience Angiotensin II Rats Inbred Strains Preoptic Area Rats Preoptic area Endocrinology medicine.anatomical_structure Catecholamine Neurology (clinical) medicine.symptom Pharmaceutical Vehicles business hormones hormone substitutes and hormone antagonists Developmental Biology medicine.drug |
Zdroj: | Brain research. 558(1) |
ISSN: | 0006-8993 |
Popis: | Adult male Sprague-Dawley rats were injected with either 6-hydroxydopamine (6-OHDA) or vehicle in the median preoptic nucleus and the organum vasculosum of the lamina terminalis. The subjects were tested for drinking responses to intraventricular angiotensin II (ANG II) or saline during either saline or norepinephrine intraventricular infusions. Rats injected with 6-OHDA into the ventral lamina terminalis initially failed to show drinking responses to ANG II injections. However, norepinephrine infusion in combination with ANG II injection restored the drinking response to ANG II in rats with catecholamine depletions of the lamina terminalis region. |
Databáze: | OpenAIRE |
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