Serum vascular endothelial growth factors C and D as forecast tools for patients with gallbladder carcinoma
| Autor: | Lei Jiang, Yanling Chen, Hai-Jie Hong, Liang-Yi Zhou, Ze-Wu Meng, Qiang Du, Feifei She, Min-Chao Liu |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
Adult
Male Lymph nodes metastases medicine.medical_specialty Pathology Cancer Research Vascular Endothelial Growth Factor C Vascular Endothelial Growth Factor D Kaplan-Meier Estimate Gastroenterology chemistry.chemical_compound Internal medicine Biomarkers Tumor medicine Carcinoma Humans Stage (cooking) Aged Aged 80 and over Serum VEGF-D Endothelial Growth Factors Serum VEGF-C Cholesterol business.industry Gallbladder Cancer General Medicine Middle Aged Prognosis medicine.disease medicine.anatomical_structure chemistry Vascular endothelial growth factor C Biliary tract Lymphatic Metastasis Preoperative Period Female Gallbladder Neoplasms Gallbladder carcinoma business Research Article |
| Zdroj: | Tumour Biology |
| ISSN: | 1010-4283 |
| DOI: | 10.1007/s13277-015-3316-3 |
| Popis: | Gallbladder carcinoma (GBC) is the most common cancer of the biliary tract. Lymph node metastasis (LNM) is the major diffusion route of GBC and is a prognosis factor. The aim of study was to assess the potential of the serum VEGF-C and VEGF-D (sVEGF-C/D) levels to predict the presence of LNM and the survival of GBC patients. The preoperative sVEGF-C/D levels of 31 patients with GBC, 10 patients with cholesterol polyps, and 10 healthy volunteers were measured by enzyme-linked immunoadsorbent assay (ELISA). The sVEGF-C/D levels of patients with GBC were significantly higher than those of people with healthy gallbladders (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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