The Immunomodulating Effect of Phlorotannins from a Brown Alga, Eisenia nipponica, on Mice Stimulated with Ovalbumin through T Cell Regulation

Autor: Yoshimasa Sugiura, Yuta Matsuura, Hirotaka Katsuzaki, Makoto Kakinuma, Hideomi Amano, Masakatsu Usui, Ryusuke Tanaka, Teruo Matsushita, Masaaki Miyata
Rok vydání: 2022
Předmět:
Zdroj: Plant foods for human nutrition (Dordrecht, Netherlands). 77(2)
ISSN: 1573-9104
Popis: The immunomodulating effect of phlorotannin was investigated in mice stimulated by ovalbumin. When analyzing the main components of phlorotannin concentrate (PTC) from Eisenia nipponica, seven phlorotannins [eckol, 6,6'-bieckol, 6,8'-bieckol, 8,8'-bieckol, dieckol, phlorofucofuroeckol (PFF)-A, and PFF-B] were detected. These phlorotannins accounted for approximately 80% of PTC. Oral administration of PTC to mice daily for 21 days reduced serum immunoglobulin E (IgE) and total IgG
Databáze: OpenAIRE