The Immunomodulating Effect of Phlorotannins from a Brown Alga, Eisenia nipponica, on Mice Stimulated with Ovalbumin through T Cell Regulation
Autor: | Yoshimasa Sugiura, Yuta Matsuura, Hirotaka Katsuzaki, Makoto Kakinuma, Hideomi Amano, Masakatsu Usui, Ryusuke Tanaka, Teruo Matsushita, Masaaki Miyata |
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Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Plant foods for human nutrition (Dordrecht, Netherlands). 77(2) |
ISSN: | 1573-9104 |
Popis: | The immunomodulating effect of phlorotannin was investigated in mice stimulated by ovalbumin. When analyzing the main components of phlorotannin concentrate (PTC) from Eisenia nipponica, seven phlorotannins [eckol, 6,6'-bieckol, 6,8'-bieckol, 8,8'-bieckol, dieckol, phlorofucofuroeckol (PFF)-A, and PFF-B] were detected. These phlorotannins accounted for approximately 80% of PTC. Oral administration of PTC to mice daily for 21 days reduced serum immunoglobulin E (IgE) and total IgG |
Databáze: | OpenAIRE |
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