The cloning, phylogenetic relationship and distribution pattern of two new putative GPCR-type octopamine receptors in the desert locust (Schistocerca gregaria)
| Autor: | Rut Vleugels, Jozef Vanden Broeck, Heleen Verlinden, Liesbeth Badisco, Elisabeth Marchal, Hans-Joachim Pflüger, Julie Tobback, Wolfgang Blenau |
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| Rok vydání: | 2010 |
| Předmět: |
Central Nervous System
Male Physiology media_common.quotation_subject Central nervous system Grasshoppers Insect Receptors G-Protein-Coupled chemistry.chemical_compound Receptors Biogenic Amine Biogenic amine medicine Animals Cloning Molecular Muscle Skeletal Receptor Neurotransmitter Desert locust Institut für Biochemie und Biologie Phylogeny DNA Primers media_common G protein-coupled receptor chemistry.chemical_classification Life Cycle Stages biology Reverse Transcriptase Polymerase Chain Reaction Ecology Gene Expression Profiling biology.organism_classification Cell biology medicine.anatomical_structure chemistry Insect Science Female Schistocerca |
| Zdroj: | Journal of Insect Physiology. 56:868-875 |
| ISSN: | 0022-1910 |
| DOI: | 10.1016/j.jinsphys.2010.03.003 |
| Popis: | The biogenic amine octopamine functions as a neuromodulator, neurotransmitter and neurohormone in insect nervous systems. It plays a prominent role in modulating multiple physiological and behavioural processes in invertebrates. Octopamine exerts its effects by binding to specific receptor proteins that belong to the superfamily of G protein-coupled receptors. We found two partial sequences of putative octopamine receptors in the desert locust Schistocerca gregaria (SgOct alpha R and SgOct beta R) and investigated their transcript levels in males and females of both phases and during the transition between long-term solitarious and gregarious locusts. The transcript levels of SgOctaR are the highest in the central nervous system, whereas those of SgOct beta R are the highest in the flight muscles, followed by the central nervous system. Both SgOct alpha R and SgOct beta R show higher transcript levels in long-term gregarious locusts as compared to solitarious ones. The rise of SgOct beta R transcript levels already appears during the first 4 h of gregarisation, during which also the behavioural changes take place. |
| Databáze: | OpenAIRE |
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