Mediastinal extravasation of doxorubicin
| Autor: | Luis López Gómez, Ignacio Chacón López-Muñiz, María Blanca Martínez-Barbeito, Jesús Andrade Santiago, Cristina Pangua Méndez, Teresa Quintanar Verdúguez, Adolfo Blanco Jarava |
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| Rok vydání: | 2008 |
| Předmět: |
Catheterization
Central Venous Cancer Research medicine.medical_specialty medicine.medical_treatment Perforation (oil well) Antineoplastic Agents Breast Neoplasms Catheters Indwelling Superior vena cava medicine Humans Infusions Intravenous Chemotherapy business.industry Mediastinum General Medicine Middle Aged medicine.disease Mediastinitis Extravasation Surgery Pleural Effusion medicine.anatomical_structure Oncology Doxorubicin Female Complication business Central venous catheter Extravasation of Diagnostic and Therapeutic Materials |
| Zdroj: | Clinical and Translational Oncology. 10:128-130 |
| ISSN: | 1699-3055 1699-048X |
| Popis: | A 48-year-old woman with a diagnosis of breast carcinoma was treated with adjuvant chemotherapy through a central venous catheter with subcutaneous reservoir (Port-A-Cath). While doxorubicin was administered, the patient presented thoracic pain and breathing distress due to superior vena cava perforation by the central catheter and subsequent extravasation of the drug into the mediastinum. The patient recovered without sequelae with conservative therapy. Cytostatic extravasation via central catheter is an uncommon complication in clinical practice. In this paper we present the first doxorubicin extravasation through a central catheter in adults and review the only ten cases found in the literature. |
| Databáze: | OpenAIRE |
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