Impact of Respiratory Rate and Dead Space in the Current Era of Lung Protective Mechanical Ventilation

Autor: Laurent Brochard, François Lellouche, Mathieu Delorme
Přispěvatelé: Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Faculty of Medicine, Université Laval, Québec, QC, Canada., Equipe de Recherche Paramédicale sur le Handicap NeuroMoteur (ERPHAN), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay, Interdepartmental Division of Critical Care Medicine, University of Toronto, Keenan Research Centre for Biomedical Science [Toronto, ON, Canada], Li Ka Shing Knowledge Institute [Toronto, ON, Canada]-St. Michael’s Hopsital [Toronto, ON, Canada]
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Chest
Chest, American College of Chest Physicians, 2020, 158 (1), pp.45-47. ⟨10.1016/j.chest.2020.02.033⟩
ISSN: 0012-3692
DOI: 10.1016/j.chest.2020.02.033⟩
Popis: International audience; Protective ventilation should potentially be applied in most or all patients undergoing invasive mechanical ventilation.1,2 Reduction of tidal volume (VT) has progressively been incorporated over the years.3 Protective ventilation is not limited to VT reduction, however, but needs a combination of ventilator settings and associated procedures.1,4 The progressive reduction of VT has necessitated to increase the respiratory rate (RR), but no clear recommendation for setting the rate exists. In addition, the impact of dead space, including instrumental dead space (VDinstr), became highly relevant. Reducing the VDinstr should be recommended as part of lung protective ventilation,4 especially for patients requiring VT ≤ 6 mL/kg of predicted body weight (PBW).5 In this report, we reviewed data from the literature of the last 20 years to try to offer some clues to physicians on the questions of rate setting and the impact of dead space.
Databáze: OpenAIRE