Non-covalent binding and selective fluorescent sensing of dipyrone with a carbocyanine dye and cetyltrimethylammonium bromide
| Autor: | Sofia A. Zakharenkova, Mikhail K. Beklemishev, Anna S. Kriveleva, Nikolai Yu. Polovkov, Irina A. Doroshenko, Ekaterina A. Katkova, Tatyana A. Podrugina |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Analyte
Chemistry Non covalent 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Fluorescence Atomic and Molecular Physics and Optics 0104 chemical sciences Inorganic salts chemistry.chemical_compound Pulmonary surfactant Bromide Molecule General Materials Science 0210 nano-technology Instrumentation Spectroscopy Nuclear chemistry |
| Zdroj: | Methods and applications in fluorescence. 9(1) |
| ISSN: | 2050-6120 |
| Popis: | The work is aimed at the search of selective fluorescent sensors without using specific artificial receptors, antibodies, enzymes etc. With this end in view, methods based on non-covalent binding of target analytes are sought. We observed dramatic changes in the emission spectrum of a carbocyanine dye in a micellar surfactant solution (cetyltrimethylammonium bromide, CTAB) in the presence of dipyrone (metamizol, analgin): the 480 nm band intensity increases with a simultaneous decrease in intensity in near-IR region (720 nm). MALDI and NMR-1H data show the intact molecules of dipyrone and the dye. The detection can be performed in the presence of other organic species and inorganic salts. Dipyrone testing is feasible within 5 × 10–7–5 × 10–4 M with RSDs of 3.5% by using a visualizer instead of a spectrofluorimeter. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|