A systematic review and meta-analysis of intellectual, neuropsychological, and psychoeducational functioning in neurofibromatosis type 1

Autor:	Andrew J. D. Crow, Jennica M. Janssen, Carolina Marshall, Anne Moffit, Laura Brennan, Christian G. Kohler, David R. Roalf, Paul J. Moberg
Rok vydání:	2022
Předmět:	Adult Neurofibromatosis 1 Adolescent Infant Middle Aged Neuropsychological Tests Young Adult Cognition Cross-Sectional Studies Child Preschool Genetics Humans Child Cognition Disorders Genetics (clinical) Aged
Zdroj:	American journal of medical genetics. Part A. 188(8)
ISSN:	1552-4833
Popis:	Neurofibromatosis Type 1 (NF1) is a common genetic disorder frequently associated with cognitive deficits. Despite cognitive deficits being a key feature of NF1, the profile of such impairments in NF1 has been shown to be heterogeneous. Thus, we sought to quantitatively synthesize the extant literature on cognitive functioning in NF1. A random-effects meta-analysis of cross-sectional studies was carried out comparing cognitive functioning of patients with NF1 to typically developing or unaffected sibling comparison subjects of all ages. Analyses included 50 articles (Total N
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f81abec96a274a011465c0c96fd1583 https://pubmed.ncbi.nlm.nih.gov/35546306 Zobrazit plný text záznamu Plný text