Implementation of a Novel 288-Element Dual-Frequency Array for Acoustic Angiography: In Vitro and In Vivo Characterization
| Autor: | F. Stuart Foster, Guofeng Pang, Isabel G. Newsome, Jianhua Yin, Claudia Carnevale, Jing Yang, Thomas M. Kierski, Paul A. Dayton, Christine E. M. Demore, Emmanuel Cherin |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
Acoustics and Ultrasonics medicine.diagnostic_test Transducers Angiography Contrast Media Acoustics 01 natural sciences Article Ultrasonic imaging Transducer In vivo 0103 physical sciences otorhinolaryngologic diseases Ultrasound imaging medicine Dual frequency Sensitivity (control systems) Electrical and Electronic Engineering 010301 acoustics Instrumentation Ultrasonography Biomedical engineering |
| Zdroj: | IEEE Trans Ultrason Ferroelectr Freq Control |
| ISSN: | 1525-8955 0885-3010 |
| Popis: | Acoustic angiography is a superharmonic contrast-enhanced ultrasound imaging method that produces high-resolution, three-dimensional maps of the microvasculature. Previous acoustic angiography studies have used two-element, annular, mechanically actuated transducers (called “wobblers”) to image microvasculature in preclinical tumor models with high contrast-to-tissue ratio and resolution, but these early wobbler transducers could not achieve the depth and sensitivity required for clinical acoustic angiography. In this work, we present a system for performing acoustic angiography with a novel dual-frequency transducer – a coaxially stacked dual-frequency array. We evaluate the dual-frequency array system both in vitro and in vivo and demonstrate improvements in sensitivity and imaging depth up to 13.1 dB and 10 mm, respectively, compared to previous wobbler probes. |
| Databáze: | OpenAIRE |
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