The clinical value of single photon emission computed tomography myocardial perfusion imaging in cardiac risk stratification of very elderly patients (≥80 years) with suspected coronary artery disease
| Autor: | Shishir Mathur, Gary V. Heller, Sanjeev U. Nair, Alan W. Ahlberg, Donna M. Polk, Deborah Katten |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Frail Elderly medicine.medical_treatment Comorbidity Coronary Artery Disease Single-photon emission computed tomography Revascularization Risk Assessment Sensitivity and Specificity Coronary artery disease Young Adult Myocardial perfusion imaging Risk Factors Internal medicine Prevalence medicine Humans Radiology Nuclear Medicine and imaging Myocardial infarction Geriatric Assessment Survival rate Aged Cardiac catheterization Aged 80 and over Tomography Emission-Computed Single-Photon medicine.diagnostic_test business.industry Myocardial Perfusion Imaging Reproducibility of Results Middle Aged medicine.disease Survival Analysis Survival Rate SSS Connecticut Cardiology Female Radiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Nuclear Cardiology. 19:244-255 |
| ISSN: | 1532-6551 1071-3581 |
| DOI: | 10.1007/s12350-011-9477-6 |
| Popis: | The role of single photon emission computed tomography myocardial perfusion imaging (SPECT MPI) in cardiac evaluation of the very elderly patients is unclear. We investigated the clinical value of SPECT MPI in very elderly patients (≥80 years) with suspected coronary artery disease (CAD) as well as in comparison to younger patients. A retrospective analysis of prospectively collected data from 8,864 patients [1,093 patients ≥80 years (very elderly), 3,369 patients 65-79 years (elderly), and 4,402 patients 50-64 years (middle-aged)] with suspected CAD who underwent exercise and/or pharmacologic stress testing with SPECT MPI between 1996 and 2005 was performed. Clinical and SPECT MPI characteristics, cardiac event rates, early (≤60 days) cardiac catheterization and revascularization rates of very elderly patients were compared to that of younger patients. Mean follow-up for cardiac events (cardiac death or non-fatal myocardial infarction) was 1.9 ± 0.9 years. Very elderly patients with moderate to severely abnormal SSS had a significantly higher annualized cardiac event rate than those with mildly abnormal or normal study (9.6% vs 3.4% and 2.5% respectively, P |
| Databáze: | OpenAIRE |
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