The effects of mandibular advancement appliance therapy on the sequence of jaw-closing muscle activity and respiratory events in individuals with obstructive sleep apnea

Autor: Deshui Li, Ghizlane Aarab, Frank Lobbezoo, Patrick Arcache, Gilles J. Lavigne, Nelly Huynh
Přispěvatelé: Oral Kinesiology
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Sleep and breathing, 27(2), 757-764. Springer Verlag
Li, D, Aarab, G, Lobbezoo, F, Arcache, P, Lavigne, G J & Huynh, N 2022, ' The effects of mandibular advancement appliance therapy on the sequence of jaw-closing muscle activity and respiratory events in individuals with obstructive sleep apnea ', Sleep and breathing, vol. 27, no. 2, pp. 757-764 . https://doi.org/10.1007/s11325-022-02624-z
ISSN: 0201-1425
1520-9512
Popis: Purpose To determine the effects of a mandibular advancement appliance (MAA) on sequences of jaw-closing muscle activity (JCMA) and apneic or hypopneic event (AHE) in individuals with obstructive sleep apnea (OSA). Methods Individuals with OSA were included in a secondary analysis of a randomized controlled crossover trial, in which two ambulatory polysomnographic recordings were performed: one with MAA in situ and the other without MAA. A time span of 16 s between JCMA and AHE was applied to classify JCMAs into four sequences: (1) JCMA occurs before AHE (B-type); (2) both events occur simultaneously (S-type); (3) JCMA occurs after AHE (A-type); and (4) JCMA is time-unrelated to AHE (U-type). The effects of MAA on the distribution of these sequences were analyzed by Wilcoxon signed-rank test. Results Among 16 individuals (10 men, mean age 51.3 ± 8.5 years) baseline apnea–hypopnea index and JCMA index were 23.8 ± 16.0 events/h and 10.8 ± 10.3 events/h, respectively. In both conditions, i.e., without and with MAA, most JCMAs were U-type (48% and 65%, respectively), followed by A-type (41% and 22%), B-type (25% and 21%), and S-type (2% and 1%). With MAA in situ, only the A-type JCMA index decreased significantly (P = 0.005), while B-type, S-type, and U-type JCMA indices did not change significantly (all P > 0.05). Conclusion MAA therapy only significantly reduces the jaw-closing muscle activities that occur after apneic or hypopneic events in individuals with OSA. Trial registration www.clinicaltrials.gov (NCT02011425); December 13, 2013.
Databáze: OpenAIRE
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