Dysgeusia and Dysosmia in Chronic Kidney Disease: NHANES 2011-2014
| Autor: | Yasaswi V. Vengalasetti, Rita Popat, Glenn M. Chertow |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
National Health and Nutrition Examination Survey Medicine (miscellaneous) Renal function urologic and male genital diseases Dysgeusia Olfaction Disorders Diabetes mellitus Internal medicine medicine Humans Renal Insufficiency Chronic Nutrition and Dietetics business.industry Odds ratio medicine.disease Nutrition Surveys Dysosmia female genital diseases and pregnancy complications Confidence interval Cross-Sectional Studies Nephrology Chronic Disease medicine.symptom business Kidney disease Glomerular Filtration Rate |
| Zdroj: | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. 32(5) |
| ISSN: | 1532-8503 |
| Popis: | Background Dysgeusia and dysosmia are known to be associated with end-stage renal disease. Whether dysgeusia and dysosmia are associated with non-dialysis-requiring chronic kidney disease (CKD) is unknown. Methods We utilized data from the National Health and Nutrition Examination Survey (NHANES) years 2011-14. We classified CKD by stage using standard criteria for estimated glomerular filtration rate (eGFR) and the albumin-to-creatinine ratio (UACR). We employed multivariable logistic regression analysis to determine the independent associations among CKD, CKD stage, and dysgeusia and dysosmia using a ChemoSensory questionnaire. Results After adjusting for the residual effects of age, sex, self-reported race, and diabetes, non-dialysis-requiring CKD was significantly associated with dysgeusia (odds ratio (OR), 95% confidence interval) 1.34 (1.05, 1.70); the association with dysosmia was of borderline significance OR 1.27 (0.97, 1.68). Odds of dysgeusia were higher at more severe CKD stages. Conclusion Non-dialysis-requiring CKD is significantly associated with self-reported dysgeusia. |
| Databáze: | OpenAIRE |
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