The fates of the callosal neurons in neocortex after bisection of the corpus callosum, using the technique of retrograde neuronal labeling with two fluorescent dyes
Autor: | M. Kishikawa, Y.I. Orihara, Kenji Ono |
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Rok vydání: | 1997 |
Předmět: |
Male
Bisection Amidines Posterior parietal cortex Neocortex Corpus callosum Functional Laterality Corpus Callosum Neural Pathways medicine Animals Rats Wistar Axon Molecular Biology Fluorescent Dyes Epilepsy General Neuroscience Anatomy Rats medicine.anatomical_structure nervous system Neurology (clinical) Psychology Neuroscience Developmental Biology |
Zdroj: | Brain Research. 778:393-396 |
ISSN: | 0006-8993 |
DOI: | 10.1016/s0006-8993(97)01023-8 |
Popis: | The fate of callosal neurons after callosotomy is yet unclear although this has become a common surgical procedure for intractable generalized epilepsies. Using retrograde neuronal labeling with two fluorescent dyes, we demonstrated that callosal neurons in the parietal cortex of the adult rat survive up to 20 weeks after callosotomy. Our data suggest that these neurons possess numerous ipsilateral axon collaterals with indispensable functions in the ipsilateral hemisphere. |
Databáze: | OpenAIRE |
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