Cardiometabolic profile of obese children in a sub-Saharan African setting: a cross-sectional study

Autor: Daniel Nebongo, Olivier Koki Ndombo, Suzanne Sap, Issa Ngosso Tetanye, Simeon-Pierre Choukem, Eunice Chedjou-Nono
Rok vydání: 2016
Předmět:
Male
Pediatrics
medicine.medical_specialty
Pediatric Obesity
Waist
Abdominal Obesity
Adolescent
Cross-sectional study
Hypercholesterolemia
Obese Child
Type 2 diabetes
030204 cardiovascular system & hematology
Childhood obesity
Body Mass Index
03 medical and health sciences
0302 clinical medicine
Classification of obesity
medicine
Prevalence
Humans
030212 general & internal medicine
Acanthosis Nigricans
Cameroon
Child
Acanthosis nigricans
Abdominal obesity
Normal Body Mass Index
Metabolic Syndrome
business.industry
lcsh:RJ1-570
lcsh:Pediatrics
medicine.disease
Obesity
Cross-Sectional Studies
Diabetes Mellitus
Type 2
High Density Lipoprotein Cholesterol Level
Case-Control Studies
Child
Preschool
Pediatrics
Perinatology and Child Health
Hypertension
Female
medicine.symptom
Waist Circumference
business
Research Article
Zdroj: BMC Pediatrics
BMC Pediatrics, Vol 17, Iss 1, Pp 1-6 (2017)
ISSN: 1471-2431
Popis: Background Cardiovascular and metabolic consequences of obesity in children, unlike adults, are still not well understood nor have they been subject to extensive research in Africa. We aimed to identify the cardio-metabolic complications associated with childhood obesity at the early phase of the management of obese children in a reference center in Cameroon. Methods In this cross-sectional study conducted from November 2013 to September 2014 and based on World Health Organization (WHO) classification of Obesity (BMI > 3SD under 5 years and BMI > 2SD from 5 and above), we included children aged 3 to 17 years who were being followed up for obesity at the pediatric endocrinology unit of the Mother and Child Center of the Chantal BIYA Foundation in Yaounde, Cameroon. A control group composed of children with normal BMI coming for a routine check up or vaccination was matched to the obese subjects. In both groups, we measured waist circumference (WC), blood pressure, fasting lipid profile and fasting glycaemia. We also considered the presence or absence of acanthosis nigricans. Data were analyzed using STATA software version 11.0, and presented as means, medians, compared with parametric and non-parametric statistical tests. Results We enrolled 38 obese children and 38 controls matched for sex and age. The majority of our participants were boys with a sex ratio of 1.24, and median age was 9.9 years. The median Z score of BMI was 3.21 in obese children. Approximately (n = 35) 90% of obese children ( 0.5) and 58% (n = 22) had acanthosis nigricans (5% (n = 2) in controls, p 10 years. Conclusions Obesity in children is associated with early onset metabolic disorders such as dyslipidemia, high blood pressure and type 2 diabetes. The screening and management of these complications is therefore recommended.
Databáze: OpenAIRE
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