Risk Factors and Outcomes of Hospital Acquired Pneumonia in Young Bangladeshi Children
| Autor: | Lubaba Shahrin, Mostafa Taufiq Ahmed, K. M. Shahunja, Shafiul Islam, Mst. Mahmuda Ackhter, Ishrat Jahan Karim, Tahmeed Ahmed, Mohammod Jobayer Chisti, Haimanti Saha, Md. Tanveer Faruk, Abu Sadat Mohammad Sayeem Bin Shahid, Irin Parvin, Tahmina Alam |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Persistent diarrhea
Pediatrics medicine.medical_specialty Science Severe Acute Malnutrition severe acute malnutrition Hospital-acquired pneumonia General Biochemistry Genetics and Molecular Biology Article Hypoxemia stomatognathic system children medicine risk factors bacteremia Ecology Evolution Behavior and Systematics Bangladesh hypoxemia business.industry High mortality Paleontology medicine.disease persistent diarrhea hospital acquired pneumonia Space and Planetary Science Bacteremia outcome medicine.symptom business Limited resources |
| Zdroj: | Life Life, Vol 11, Iss 1030, p 1030 (2021) Volume 11 Issue 10 |
| ISSN: | 2075-1729 |
| Popis: | Hospital acquired pneumonia (HAP) is common and often associated with high mortality in children aged five or less. We sought to evaluate the risk factors and outcome of HAP in such children. We compared demographic, clinical, and laboratory characteristics in children < 5 years using a case control design during the period of August 2013 and December 2017, where children with HAP were constituted as cases (n = 281) and twice as many randomly selected children without HAP were constituted as controls (n = 562). HAP was defined as a child developing a new episode of pneumonia both clinically and radiologically after at least 48 h of hospitalization. A total of 4101 children were treated during the study period. The mortality was significantly higher among the cases than the controls (8% vs. 4%, p = 0.014). In multivariate logistic regression analysis, after adjusting for potential confounders, it was found that persistent diarrhea (95% CI = 1.32–5.79 p = 0.007), severe acute malnutrition (95% CI = 1.46–3.27 p < 0.001), bacteremia (95% CI = 1.16–3.49 p = 0.013), and prolonged hospitalization of > 5 days (95% CI = 3.01–8.02 0.001) were identified as independent risk factors for HAP. Early identification of these risk factors and their prompt management may help to reduce HAP-related fatal consequences, especially in resource limited settings. |
| Databáze: | OpenAIRE |
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