Fluorescence-based bowel anastomosis perfusion evaluation: results from the IHU-IRCAD-EAES EURO-FIGS registry

Autor: Jan Grosek, Laurents P. S. Stassen, Andrea Balla, Davide Cosola, Catalin Copaescu, Silvia Quaresima, Maurizio Castagnola, Giuseppe Navarra, Paolo De Paolis, Gonzalo P Martin-Martin, Andrea Picchetto, Ivano Dal Dosso, J. Kosir, Marcello Calabrò, Harmony Impellizzeri, Roland Chautems, Carlo Castoro, Mahdi Al-Taher, Gian Luca Baiocchi, Giancarlo D'Ambrosio, G. Moretto, Giovanni Maria Garbarino, Giorgio Bianchi, Giuseppe Spinoglio, Alessandro Franchello, Robert Juvan, Salvador Morales Conde, Carlos Marques Ferreira, Emilio Bertani, Marco Filauro, Nunzio Rosso, Antonio Pesce, Gabriele Anania, Andrea Spota, Lorenzo Casali, Ramon Vilallonga, Marc Olivier Sauvain, Christian Franzini, Orestis Ioannidis, Michele Diana, Eleftherios Gialamas, Alend Saadi, Eric Felli, Gaetano La Greca, Jacques Marescaux, Paola De Nardi, José F. Noguera, Alessio Rollo, Pietro Riva, Nicolò de Manzini, Marta Silvestri, Caterina Santi, Luciano Tartamella, Gregor Norčič, Alessandro Patané, Thomas Carus, Alessandro M. Paganini, Luigi Boni
Přispěvatelé: Surgery, MUMC+: MA Heelkunde (9), MUMC+: MA AIOS Heelkunde (9), RS: NUTRIM - R2 - Liver and digestive health, RS: SHE - R1 - Research (OvO), Spota, A., Al-Taher, M., Felli, E., Morales Conde, S., Dal Dosso, I., Moretto, G., Spinoglio, G., Baiocchi, G., Vilallonga, R., Impellizzeri, H., Martin-Martin, G. P., Casali, L., Franzini, C., Silvestri, M., de Manzini, N., Castagnola, M., Filauro, M., Cosola, D., Copaescu, C., Garbarino, G. M., Pesce, A., Calabro, M., de Nardi, P., Anania, G., Carus, T., Boni, L., Patane, A., Santi, C., Saadi, A., Rollo, A., Chautems, R., Noguera, J., Grosek, J., D'Ambrosio, G., Ferreira, C. M., Norcic, G., Navarra, G., Riva, P., Quaresima, S., Paganini, A., Rosso, N., De Paolis, P., Balla, A., Sauvain, M. O., Gialamas, E., Bianchi, G., La Greca, G., Castoro, C., Picchetto, A., Franchello, A., Tartamella, L., Juvan, R., Ioannidis, O., Kosir, J. A., Bertani, E., Stassen, L., Marescaux, J., Diana, M.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
medicine.medical_specialty
Registry
RESECTION
INDOCYANINE GREEN
Subgroup analysis
Anastomotic Leak
Near-infrared fluorescence imaging
Anastomosis
Anastomotic leakage (AL) is one of the dreaded complications following surgery in the digestive tract. Nearinfrared fluorescence (NIRF) imaging is a means to intraoperatively visualize anastomotic perfusion
NO
03 medical and health sciences
COLORECTAL-SURGERY
ESOPHAGECTOMY
0302 clinical medicine
LEAKAGE
Statistical significance
Internal medicine
medicine
Humans
Image-guided surgery
Registries
Anastomotic leakage (AL) is one of the dreaded complications following surgery in the digestive tract. Nearinfrared fluorescence (NIRF) imaging is a means to intraoperatively visualize anastomotic perfusion
facilitating fluorescence image-guided surgery (FIGS) with the purpose to reduce the incidence of AL. The aim of this study was to analyze the current practices and results of NIRF imaging of the anastomosis in digestive tract surgery through the EURO-FIGS registry
COMPLICATIONS
CONSEQUENCES
business.industry
Incidence (epidemiology)
Anastomosis
Surgical
Hepatology
CANCER
facilitating fluorescence image-guided surgery (FIGS) with the purpose to reduce the incidence of AL. The aim of this study was to analyze the current practices and results of NIRF imaging of the anastomosis in digestive tract surgery through the EURO-FIGS registry
Perfusion
Surgery
Computer-Assisted
030220 oncology & carcinogenesis
RISK-FACTORS
fluorescence-guided surgery
image-guided surgery
near-infrared fluorescence imaging
registry
Fluorescence-guided surgery
030211 gastroenterology & hepatology
Surgery
Radiology
ENHANCED REALITY
business
Abdominal surgery
Zdroj: Surgical endoscopy and other interventional techniques, 35(12), 7142-7153. Springer, Cham
ISSN: 0930-2794
Popis: Background: Anastomotic leakage (AL) is one of the dreaded complications following surgery in the digestive tract. Near-infrared fluorescence (NIRF) imaging is a means to intraoperatively visualize anastomotic perfusion, facilitating fluorescence image-guided surgery (FIGS) with the purpose to reduce the incidence of AL. The aim of this study was to analyze the current practices and results of NIRF imaging of the anastomosis in digestive tract surgery through the EURO-FIGS registry. Methods: Analysis of data prospectively collected by the registry members provided patient and procedural data along with the ICG dose, timing, and consequences of NIRF imaging. Among the included upper-GI, colorectal, and bariatric surgeries, subgroup analysis was performed to identify risk factors associated with complications. Results: A total of 1240 patients were included in the study. The included patients, 74.8% of whom were operated on for cancer, originated from 8 European countries and 30 hospitals. A total of 54 surgeons performed the procedures. In 83.8% of cases, a pre-anastomotic ICG dose was administered, and in 60.1% of cases, a post-anastomotic ICG dose was administered. A significant difference (p < 0.001) was found in the ICG dose given in the four pathology groups registered (range: 0.013–0.89mg/kg) and a significant (p < 0.001) negative correlation was found between the ICG dose and BMI. In 27.3% of the procedures, the choice of the anastomotic level was guided by means of NIRF imaging which means that in these cases NIRF imaging changed the level of anastomosis which was first decided based on visual findings in conventional white light imaging. In 98.7% of the procedures, the use of ICG partly or strongly provided a sense of confidence about the anastomosis. A total of 133 complications occurred, without any statistical significance in the incidence of complications in the anastomoses, whether they were ICG-guided or not. Conclusion: The EURO-FIGS registry provides an insight into the current clinical practice across Europe with respect to NIRF imaging of anastomotic perfusion during digestive tract surgery.
Databáze: OpenAIRE
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