Alcohol flushing is independently associated with lesser degree of carotid atherosclerosis in Japanese type 2 diabetic patients
| Autor: | Mai Hashizume, Fumiko Otsuka, Go Koizumi, Shoichiro Nagasaka, Ryo Saiki, Toru Iizaka, Kei Endo, Rie Tadokoro, Masahiko Izumizaki, Norimitsu Murai, Yasuyoshi Kigawa |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Aldehyde dehydrogenase 030209 endocrinology & metabolism Alcohol Type 2 diabetes 030204 cardiovascular system & hematology Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Diabetes mellitus Internal Medicine medicine Risk factor biology business.industry Type 2 Diabetes Mellitus medicine.disease Endocrinology Intima-media thickness chemistry biology.protein Flushing Original Article medicine.symptom business |
| Popis: | Type 2 diabetes mellitus is a well-known risk factor for atherosclerosis. Intima media thickness (IMT) of the carotid arteries has been widely used for assessing atherosclerotic changes representing cerebro-cardiovascular disease risk. Previous studies have associated the presence of inactive aldehyde dehydrogenase with progression of atherosclerosis and alcohol flushing. However, reports conflict on whether alcohol flushing could potentially modify the degree of atherosclerosis in type 2 diabetic patients. We retrospectively assessed the relationships among alcohol flushing, IMT, and clinical characteristics in 123 consecutive Japanese type 2 diabetic patients. Alcohol flushing was assessed by standardized questionnaires. Patients with alcohol flushing had lower mean IMT [0.7 (0.65–0.80) vs. 0.8 (0.73–0.90) mm, p |
| Databáze: | OpenAIRE |
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