Reactivity to a 35% CO2 challenge in healthy first-degree relatives of patients with panic disorder
Autor: | Nicole van Beek, Eric Griez |
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Rok vydání: | 2000 |
Předmět: |
Adult
Male medicine.medical_specialty Adolescent behavioral disciplines and activities Age and gender Internal medicine mental disorders Healthy control medicine Humans First-degree relatives Reactivity (psychology) Psychiatry Biological Psychiatry Psychiatric Status Rating Scales Panic disorder Panic Carbon Dioxide Middle Aged medicine.disease Control subjects Panic Disorder Female medicine.symptom Psychology Anxiety disorder |
Zdroj: | Biological psychiatry. 47(9) |
ISSN: | 0006-3223 |
Popis: | Background: The effects of a 35% CO 2 challenge were examined in healthy first-degree relatives of panic disorder patients and in healthy control subjects matched for age and gender. Methods: One single inhalation of a 35% CO 2 /65% O 2 challenge was administered to 50 first-degree relatives of panic disorder patients and 50 control subjects. Results: The first-degree relatives were more reactive to the 35% CO 2 challenge than the control subjects. Conclusions: These findings indicate that being a member of a family with a panic disorder patient is, in itself, an important factor in CO 2 hypersensitivity among subjects who have never experienced a panic attack. Both panic disorder patients and their first-degree relatives have a tendency to be more reactive to the CO 2 challenge. |
Databáze: | OpenAIRE |
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