Treatment of Fulminant Giant Cell Myocarditis Associated with Polymyositis Using a Left Ventricular Assist Device and Subsequent Corticosteroid and Immunosuppressive Therapy Leading to Remission
| Autor: | Hidekazu Tanaka, Ryo Takeshige, Yukio Tsuji, Ken-ichi Hirata, Hiroshi Tanaka, Junichi Ooka, Kensuke Matsumoto, Shumpei Mori, Shigeo Hara, Yutaka Okita, Yutaka Hatani |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Fulminant corticosteroid therapy immunosuppressive therapy Shock Cardiogenic Case Report 030204 cardiovascular system & hematology Giant Cells Polymyositis Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Internal medicine left ventricular assist device Internal Medicine Humans Medicine 030212 general & internal medicine Glucocorticoids Ejection fraction business.industry Myocardium Cardiogenic shock Remission Induction Muscle weakness General Medicine Myocardial contusion Middle Aged medicine.disease Myocarditis Giant cell Ventricular assist device Cardiology fulminant giant cell myocarditis Drug Therapy Combination Heart-Assist Devices medicine.symptom business Immunosuppressive Agents |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.8639-16 |
| Popis: | A 58-year-old man with a recent history of generalized myalgia and muscle weakness was transferred to our hospital because of acute progressive dyspnea. The patient underwent left ventricular (LV) assist device (LVAD) implantation due to cardiogenic shock with a LV ejection fraction (LVEF) of 6%. The histological findings obtained from LV apex showed the infiltration of multinucleated giant cells and severe myocardial contusion. Combining this histological finding with our experienced neurologists comments, resulted in a final diagnosis of fulminant giant cell myocarditis associated with polymyositis. A day after LVAD implantation, the patient received corticosteroid and immunosuppressive therapy, and the LVEF recovered to 68%. |
| Databáze: | OpenAIRE |
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