Outcome after craniotomy for recurrent cranial metastases
| Autor: | Oliver Kennion, Damian Holliman |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty medicine.medical_treatment Tumor resection Metastasis 03 medical and health sciences 0302 clinical medicine Patient age medicine Recurrent disease Humans Prospective Studies Pathological Craniotomy Aged Retrospective Studies Proportional hazards model business.industry Brain Neoplasms Retrospective cohort study General Medicine Middle Aged medicine.disease Surgery Treatment Outcome 030220 oncology & carcinogenesis Female Neurology (clinical) Neoplasm Recurrence Local business 030217 neurology & neurosurgery |
| Zdroj: | British journal of neurosurgery. 31(3) |
| ISSN: | 1360-046X |
| Popis: | To investigate the outcomes of patients with recurrent/progressive cranial metastases who underwent re-do craniotomy and to assess the utility of surgery as a treatment option.A retrospective study was conducted assessing survival after re-do craniotomy for recurrent or progressive cranial metastases. 29 patients were identified between January 2006 and December 2013. Data was gathered from a prospective pathology database, patients' notes and electronic records. The diagnosis of cranial metastasis was obtained through pathological analysis at the time of tumour resection. Results were analysed with Cox regression tests and converted into a Kaplan-Meier curve.Median patient age was 57 years old (range 24-74 years) at diagnosis of brain metastases. Two patients had serious complications after re-do surgery. Five patients had2 craniotomies for recurrent disease. Median survival after the first craniotomy was 18 months (range 4.1-50.9 months). Median survival after re-do craniotomy was 7.6 months (range 0.2-31.3 months). 90% of patients survived at least 3 months after re-do surgery, 65.5% survived at least 6 months.This study suggests that re-do surgery is a viable treatment option for patients with recurrent cranial metastases. |
| Databáze: | OpenAIRE |
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