Oxygen transport and utilization in hyperoxia and hypoxia
| Autor: | Helene Ehrlich, William C. Shoemaker, Stephen F. McCartney, C. Ray, Stanley Fink |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Hyperoxia
Cardiac output Surface oxygen business.industry Hemodynamics Oxygen transport chemistry.chemical_element Biological Transport Hypoxia (medical) Critical Care and Intensive Care Medicine Oxygen Dogs Oxygen Consumption chemistry Anesthesia medicine Animals medicine.symptom Transcutaneous oxygen Hypoxia business Conjunctiva Monitoring Physiologic |
| Zdroj: | Critical Care Medicine. 12:943-948 |
| ISSN: | 0090-3493 |
| DOI: | 10.1097/00003246-198411000-00004 |
| Popis: | A device to measure surface oxygen tension of the palpebral conjunctiva (PcjO2) was developed and tested in 12 mongrel dogs subjected to normoxia, hyperoxia, and hypoxia. Intravascular pressure, hemodynamic, and bulk oxygen transport variables were measured simultaneously with PcjO2 and transcutaneous O2 (PtcO2) and CO2 (PtcCO2). PcjO2 closely paralleled PaO2 as the fractional inspired O2 concentration was changed from 0.21 up to 1.0 and down to 0.05; the correlation coefficient, r, was 0.95 for 305 data sets. During hyperoxia there were no significant hemodynamic or bulk O2 transport changes, but during hypoxia, the cardiac output and O2 extraction increased while PaO2, PtcO2 and PcjO2 fell; O2 delivery and O2 consumption were maintained until just before death. |
| Databáze: | OpenAIRE |
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