Corneal Biomechanical Properties in Aspirin Users
Autor: | Ayse Ebru Kilavuzoglu, Cemile Banu Cosar, Ali Riza Cenk Celebi, Uğur Altiparmak |
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Rok vydání: | 2016 |
Předmět: |
Male
0301 basic medicine medicine.medical_specialty Intraocular pressure genetic structures Cornea Corneal hysteresis Tonometry Ocular 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Ophthalmology Diabetes mellitus medicine Humans Intraocular Pressure Aged Aspirin business.industry Anti-Inflammatory Agents Non-Steroidal Case-control study General Medicine Middle Aged medicine.disease Elasticity eye diseases Sensory Systems Biomechanical Phenomena Surgery 030104 developmental biology medicine.anatomical_structure Case-Control Studies Correlation analysis 030221 ophthalmology & optometry Population study Female sense organs business medicine.drug |
Zdroj: | Ophthalmic Research. 55:199-204 |
ISSN: | 1423-0259 0030-3747 |
DOI: | 10.1159/000443892 |
Popis: | Purpose: To analyze corneal biomechanical properties in aspirin users using an ocular response analyzer. Methods: This study included 80 eyes of 40 aspirin users and 80 eyes of 40 individuals who did not use aspirin. Corneal hysteresis (CH), the corneal resistance factor (CRF), Goldman-correlated intraocular pressure (IOPg), and corneal compensated intraocular pressure (IOPcc) were measured in all participants. The independent samples t test was used to compare measurements in the aspirin users and nonusers in the total study population, and in the diabetic patient subgroup. Pearson's correlation analysis was used to examine the relationship between the measured variables in the aspirin users and nonusers. Results: Aspirin users (59.08 ± 11.83 years) were older than nonusers (39.82 ± 12.97 years; p < 0.001). The mean CH was significantly lower in the aspirin user group than in the nonuser group (p = 0.013). Mean IOPg and mean IOPcc were also significantly higher in the aspirin user group (p = 0.027 and p = 0.002, respectively). The mean CRF was lower in the aspirin user group, but not significantly (p = 0.70). There was a positive correlation between CH and CRF (r = 0.767, p < 0.001), and between CRF and IOPg (r = 0.680, p < 0.001), and a negative correlation between CH and IOPcc (r = -0.415, p < 0.001). Conclusions: Aspirin should be taken into account when interpreting the results of corneal biomechanical measurements. |
Databáze: | OpenAIRE |
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