Association between Asian dust exposure and respiratory function in children with bronchial asthma in Nagasaki Prefecture, Japan
Autor: | Tasuku Kitajima, Takahiro Nakamura, Yuji Nishiwaki, Kazuhiro Komori, Kunio Hashimoto, Kasumi Tashiro, Masahiro Hashizume, Hideki Hasunuma, Atsushi Shimizu, Kayo Ueda, Hiroshi Odajima, Hiroyuki Moriuchi, Ayano Takeuchi |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Peak expiratory flow rate Evening Adolescent Asian dust 010501 environmental sciences 01 natural sciences 03 medical and health sciences 0302 clinical medicine Japan medicine Humans Respiratory function 030212 general & internal medicine Respiratory system Child Adverse effect Bronchial asthma Children 0105 earth and related environmental sciences Asthma Light detection Asian Dust business.industry lcsh:Public aspects of medicine Infant Newborn Public Health Environmental and Occupational Health Infant Dust lcsh:RA1-1270 Environmental Exposure General Medicine medicine.disease respiratory tract diseases Asthmatic children Child Preschool Female business Research Article |
Zdroj: | Environmental Health and Preventive Medicine, Vol 25, Iss 1, Pp 1-9 (2020) Environmental Health and Preventive Medicine |
ISSN: | 1342-078X |
Popis: | Background Studies on the adverse effects of Asian dust (AD) on respiratory function in children are scarce. The objective of this study was to examine the association between AD and respiratory function by measuring peak expiratory flow rates (PEFRs) in asthmatic children. Methods The study was carried out from March to May from 2014 through 2016. One hundred ten children with bronchial asthma were recruited from four hospitals in the Goto Islands and south Nagasaki area in Nagasaki prefecture. The parents were asked to record their children’s PEFRs every morning/evening and clinical symptoms in an asthma diary. AD was assessed from light detection and ranging data, and a linear mixed-effects model was used to estimate the effects of AD on daily PEFR. Time-stratified case-crossover analyses were performed to examine the association between AD and asthma attacks defined by reduction levels in PEFR. Results AD was detected on 11 days in the Goto Islands, and on 23 days in the south Nagasaki area. After adjusting for age, sex, temperature, and daily oxidants, we found a consistent association between AD and a 1.1% to 1.7% decrease in PEFR in the mornings and a 0.7% to 1.3% decrease in the evenings at a lag of 0 to 5 days. AD was not associated with the number of asthma attacks, respiratory symptoms, or other symptoms at any lag days examined. Conclusions Exposure to AD was associated with reduced PEFR, although the effects were not large enough to induce clinically apparent symptoms, in clinically well-controlled asthmatic children. |
Databáze: | OpenAIRE |
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