Microscopic organizing pneumonia and cellular non-specific interstitial pneumonia are widespread in macroscopically normal-appearing lung tissue in idiopathic pulmonary fibrosis
| Autor: | Nevins W. Todd, Jeffrey R. Galvin, Sergei P. Atamas, Irina G. Luzina, Ashutosh Sachdeva, Allen P. Burke |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Non-specific interstitial pneumonia Gastroenterology Article 03 medical and health sciences Idiopathic pulmonary fibrosis 0302 clinical medicine Internal medicine Humans Medicine In patient Pump thrombosis Lung Aged Transplantation business.industry Middle Aged medicine.disease Idiopathic Pulmonary Fibrosis Hemolysis 030228 respiratory system Coagulation 030220 oncology & carcinogenesis Female Surgery Organizing pneumonia Lung Diseases Interstitial Cardiology and Cardiovascular Medicine business Lung tissue circulatory and respiratory physiology |
| Zdroj: | The Journal of Heart and Lung Transplantation. 35:1367-1370 |
| ISSN: | 1053-2498 |
| Popis: | coagulation and possibly improve patients’ outcomes. As we have shown that hemolysis does not falsely elevate aPTT values, both tests should be used to characterize anti-coagulation intensity in patients with suspected pump thrombosis. In conclusion, aPTT and anti-Xa levels may be discordant in many CF-LVADs patients. In our experience, hemolysis does not falsely raise aPTT values. More studies are needed to prove the superiority of one assay over the other. For now, the decision to titrate UFH based on aPTT or anti-Xa should be carefully weighed in appropriate clinical contexts. |
| Databáze: | OpenAIRE |
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