Simultaneous infection with human herpesvirus-6 and measles virus in infants
| Autor: | Shigeru Yoshida, Takehiko Yazaki, Sadao Suga, Yoshizo Asano, Tetsushi Yoshikawa |
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| Rok vydání: | 1990 |
| Předmět: |
Paramyxoviridae
Herpesvirus 6 Human viruses Fluorescent Antibody Technique Exanthema Subitum Measles Measles virus Morbillivirus Virology medicine Humans Seroconversion biology Infant Herpesviridae Infections Fetal Blood biology.organism_classification medicine.disease Rash Infectious Diseases Immunology Female Human herpesvirus 6 medicine.symptom |
| Zdroj: | Journal of Medical Virology. 31:306-311 |
| ISSN: | 1096-9071 0146-6615 |
| DOI: | 10.1002/jmv.1890310412 |
| Popis: | Two infants (4 and 5 months of age) with a febrile episode for 3 and 5 days, respectively, developed skin rashes after the fever subsided and were diagnosed as exanthem subitum. The rash continued for 5 days followed by mild-to-moderate pigmentation. Human herpesvirus-6 and measles virus, which were confirmed by a specific immunofluorescence assay and by electron microscopy, were isolated simultaneously from blood in the acute stage of the disease but not from the convalescent stage. The titer of the herpesvirus-6 in blood was greater than that of measles. Specific serologic assays showed marked seroconversion against human herpesvirus-6 but not to measles virus. The results suggest that dual infection with human herpesvirus-6 and measles virus results in atypical exanthem subitum or modified measles with unique immunologic responses. |
| Databáze: | OpenAIRE |
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