Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives
| Autor: | Gianfranco Delle Fave, Emilio Di Giulio, Vito D. Corleto, F. Desideri, Cristiano Pagnini, F. Menasci |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
crohn's disease endoscopic score inflammatory bowel disease mucosal healing ulcerative colitis Disease Inflammatory bowel disease Gastroenterology Severity of Illness Index Endoscopy Gastrointestinal 03 medical and health sciences 0302 clinical medicine Intestinal mucosa Internal medicine Severity of illness medicine Humans Intestinal Mucosa Intensive care medicine Crohn's disease Modalities Hepatology business.industry medicine.disease Inflammatory Bowel Diseases Ulcerative colitis digestive system diseases Clinical trial 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology business |
| Popis: | The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge. To address this, several endoscopic scores have been proposed. Very few have been properly validated, and the use of such tools remains sub-optimal and is mainly restricted to clinical trials. In recent years, a growing emphasis of the concept of 'mucosal healing' as a prognostic marker and therapeutic goal has increased the need for a more accurate definition of endoscopic activity in both ulcerative colitis (UC) and Crohn's Disease (CD). In the present review, the evolution of the challenges related to endoscopic scores in IBD has been analyzed, with particular attention paid to the renewed relevance of endoscopic activity in recent years. Currently, despite the growing relevance of endoscopic activity, evaluating this activity in IBD is still a challenge. The implementation of efficacious endoscopic scores and a better definition of the absence of activity (mucosal healing) are needed. |
| Databáze: | OpenAIRE |
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